Uprising Guitar Lesson – Muse

In this Uprising guitar lesson video I will demonstrate note-for-note how to play this massive hit by Muse in it's entirety.

I will even transcribe the main keyboard melody for guitar so you can stay busy during that section as well. 🙂

Guitarist/singer Matthew Bellamy has built a reputation for himself over the past decade as one of the most innovative guitarists of his generation. "Uprising" provides a lot of cool guitar riffs to sink our teeth into so let's get started.

Be sure to tune your guitar to dropped "D" tuning before starting the lesson. That will mean tuning your guitar starting from the 6th string DADGBE.

I start the lesson off by showing you how to play the opening keyboard melody on the guitar. This melody is mostly based around D minor and A major arpeggios. It is a very catchy melody so it shouldn't take you very long to memorize how it should sound. The notes may require a bit of a fret hand stretch, but they go by slow enough that after just a short amount of practice you can nail the part pretty easily. At the end of the keyboard section comes a quick little guitar fill using unison bends. This is the first time you hear an actual guitar on the recording.

For the verse we have some basic octaves played in a very distinct rhythm. I will show you how to properly play those octaves and how to play the rhythm strumming pattern as well.

The chorus uses a very similar rhythm albeit will complete power chords to give it a fuller sound. The chords are rather simple here, you will just need to focus on the timing of all of them.

For the guitar solo we will basically have a section that repeats 3 times with a slight variation every time. The licks in this solo move around the fretboard quite a bit but once again nothing is played at a very high rate of speed. Plus, the repetitive nature of the solo makes it a great one to practice.

During the pedal tone lick of the solo I will show you a couple of different ways to pick it. One is using alternate picking and the second is using hybrid picking. I personally prefer hybrid picking for this part because it makes it much easier to play. However, there are many guitar players out there that have never done any hybrid picking at all, so do it whatever way feels the most comfortable to you.

Have fun learning this unique modern rock masterpiece by Muse!


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Uprising Guitar Lesson - Muse


  1. Danger on March 15, 2016 at 1:37 pm

    Hi Carl, absolutely awesome lesson! I especially love the tip about using hybrid picking for the double-time pedal point lick – that really saved me.
    Any chance you could do a lesson on Madness? I’d love your take on how Matt Bellamy is picking the pedal point lick in that lead… is he alternate picking each note, using hammer-ons, hybrid picking? I haven’t found any tabs or other lessons that show how; and it’s such a cool lick.

  2. Danger on March 26, 2016 at 2:43 pm

    Hi Carl, thought I’d let you know I solved the Madness question. It’s a really tough lick because it’s in groups of three notes played as 16ths, and you have to skip between the 3rd and 1st string a lot.

    I tried it with hammerons first, cuz that seemed easiest; and really got down the timing…but I knew that wasn’t right because it’s obvious he’s picking each note.

    So then I tried hybrid picking…and that worked well, except the plucked note wasn’t sounding as loudly and clearly as the picked notes, and I had to use a compressor, which really killed the tone.

    So then I tried economy picking (up-down-down). That worked great, but I found the timing a little difficult (I generally find it difficult to maintain rhythm when upstroking on the beat).

    Finally, I tried straight alternate picking. Went back and re-took your premium lessons on alternate picking with string skips…and voila, there’s the answer. Its technically the most difficult, but by far the best technique for that lick.

    So I guess this is a long- winded way of saying thanks…yet another of your lessons has paid off!!

  3. Edward lewis on June 27, 2016 at 9:38 pm

    hi Carl…my group will be rehearsing this tune soon and wanted to know if there you have tabs for this lesson.

  4. Edward lewis on June 27, 2016 at 9:41 pm

    Hi Carl, Ed again……….I see that there are laws that prohibit creating tabs.

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